S-DNA APTAMER-6

Other

58

Moderate

About S-DNA APTAMER-6

S-DNA APTAMER-6 is a cosmetic ingredient used in product formulations. Its specific function may vary depending on the product type and formulation. Exercise caution due to limited available safety data.

Detailed Analysis

S-DNA Aptamer-6 is a 33-nucleotide single-stranded DNA molecule generated through systematic evolution of ligands by exponential enrichment (SELEX). It binds specifically to Epigallocatechin Gallate (EGCG), a major polyphenol in green tea with antioxidant skin benefits. As with other DNA aptamers, it represents a novel functional ingredient category in cosmetics. EU Regulation 1223/2009 does not specifically address DNA aptamers, so safety evaluation follows general cosmetic ingredient assessment principles. The synthetic nature ensures defined structure.

Skin Benefits

  • High-affinity EGCG binding (antioxidant green tea component)
  • Potential targeted delivery or stabilization of EGCG in skin
  • Synthetic production with precise sequence control
  • Well-defined 3D structure

Known Concerns

  • Novel cosmetic ingredient with limited safety history
  • EU regulatory framework does not specifically cover DNA aptamers
  • Long-term sensitization data unavailable
  • Novel mechanism of action requires additional safety review

Safety Score

58

Moderate

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.