(Epoxyethyl)benzene (Styrene oxide)

10

Avoid

CAS Number: 96-09-3

About (Epoxyethyl)benzene (Styrene oxide)

An epoxide compound classified as a probable human carcinogen and mutagen, banned from cosmetic use in the EU due to severe genotoxicity and organ toxicity concerns.

Detailed Analysis

(Epoxyethyl)benzene, commonly known as styrene oxide (CAS 96-09-3), is an epoxide derived from styrene metabolism. EU Regulation 1223/2009 Annex III restricts its use to concentrations below 0.1% as a constituent of substances or mixtures. The compound carries extensive hazard statements including H227 (combustible), H302/H312/H332 (harmful if swallowed, in contact with skin, or if inhaled), H315/H317/H319/H335 (irritation and sensitization), H340 (may cause genetic defects), H341 (suspected of causing genetic defects), H350 (may cause cancer), H361 (suspected of reproductive toxicity), H370/H372 (organ toxicity), and H401/H412 (aquatic toxicity). It is classified as a Group 2A probable human carcinogen by IARC.

Known Concerns

  • EU Annex III restricted - probable carcinogen
  • Confirmed mutagen (H340)
  • Suspected carcinogen (H350)
  • Reproductive toxicity (H361)
  • Organ toxicity (H370/H372)
  • Extensive hazard profile

Safety Score

10

Avoid

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.