2,4,5,6-Tetraaminopyrimidine sulphate
Caution
CAS Number: 5392-28-9
About 2,4,5,6-Tetraaminopyrimidine sulphate
An oxidative hair dye intermediate used to achieve gray and blue-black shades, restricted to 3.4% maximum (calculated as sulfate) in EU hair dye formulations.
Detailed Analysis
2,4,5,6-Tetraaminopyrimidine sulfate (CAS 5392-28-9) functions as a primary intermediate in oxidative hair dyeing processes, particularly for achieving gray and blue-black shades when combined with couplers. EU Regulation 1223/2009 Annex III restricts its maximum concentration to 3.4% calculated as sulfate in hair dye products. The compound carries hazard statements H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation), indicating the need for proper handling and formulation control to minimize exposure to hairdressers and consumers.
What It Does
Skin Benefits
- ✓ Essential hair dye intermediate for gray and blue-black shades
- ✓ Used in oxidative hair coloring formulations
- ✓ Provides color development with appropriate couplers
Known Concerns
- ⚠ Maximum 3.4% concentration limit in EU (as sulfate)
- ⚠ Skin irritation hazard (H315)
- ⚠ Eye irritation hazard (H319)
- ⚠ Respiratory irritation potential (H335)
- ⚠ Occupational exposure concern for hairdressers
Safety Score
Caution
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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