6-METHOXY-2,3-PYRIDINEDIAMINE HCL

Hair Dye

55

Moderate

CAS Number: 94166-62-8

About 6-METHOXY-2,3-PYRIDINEDIAMINE HCL

An aromatic diamine hair-dye precursor (pyridinediamine class). Sensitizing like the PPD family — patch test before use.

Detailed Analysis

6-Methoxy-2,3-pyridinediamine HCl (CAS 94166-62-8) is the hydrochloride salt of a methoxylated pyridinediamine used as an oxidative coupler in hair colorants. Aromatic diamines as a class — including the pyridine-ring variants — are well-documented scalp sensitizers, and SCCS has issued opinions on several members establishing maximum use concentrations and patch-test requirements. This specific grade appears in EU CosIng for hair-dye use with concentration limits. Cross-reactivity with para-phenylenediamine-sensitized individuals is plausible. Rinse-off application with gloves and a 48-hour patch test is standard.

What It Does

HAIR DYEING

Skin Benefits

  • ✓ Enables oxidative hair coloring at low use levels

Known Concerns

  • ⚠ Aromatic-diamine sensitization risk
  • ⚠ Possible PPD cross-reactivity
  • ⚠ Concentration limits apply under SCCS opinions

Safety Score

55

Moderate

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.