S-HIV-1 OLIGOPEPTIDE-2 SP

Conditioning Agent

35

Caution

About S-HIV-1 OLIGOPEPTIDE-2 SP

A synthetic 55-amino-acid oligopeptide modeled after HIV-1 Gag-Pol polyprotein, used for skin conditioning despite major consumer acceptance challenges stemming from its viral-derived name.

Detailed Analysis

This synthetic peptide shares sequence identity with a portion of HIV-1 Gag-Pol polyprotein but is produced entirely through standard synthetic peptide chemistry with no biological materials. The SCCS has not specifically assessed this ingredient, and it is not listed in EU Annexes restricting use. However, the HIV-1 nomenclature presents serious consumer acceptance barriers and may invite regulatory review under cosmetics labeling and safety requirements. The longer sequence (55 amino acids) approaches the size range where some regulatory frameworks become more stringent.

What It Does

SKIN CONDITIONING SKIN PROTECTING

Skin Benefits

  • Skin conditioning
  • Skin protecting

Known Concerns

  • Major consumer acceptance issues due to HIV-1 nomenclature
  • Regulatory risk: potential restriction based on nomenclature and size
  • Longer peptide sequence may face enhanced safety assessment

Safety Score

35

Caution

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.