S-HIV-1 OLIGOPEPTIDE-1

Conditioning Agent

35

Caution

About S-HIV-1 OLIGOPEPTIDE-1

A synthetic peptide modelled on the HIV-1 TAT protein, raising significant regulatory concern due to its pathogenic viral origin sequence.

Detailed Analysis

A 38-amino-acid synthetic protein fragment based on the HIV-1 TAT (Transactivator of Transcription) protein sequence. While chemically synthesised and not infectious, the use of a pathogenic viral protein template is flagged by EU cosmetic safety reviewers. The EU SCCS has expressed concern about peptides derived from viral or bacterial toxins in cosmetic formulations. Restricted to very low use levels; not approved in some markets. Score reflects regulatory uncertainty and public health sensitivity.

What It Does

SKIN CONDITIONING - MISCELLANEOUS

Skin Benefits

  • Skin conditioning function reported

Known Concerns

  • Derived from pathogenic viral protein sequence — regulatory sensitivity
  • EU SCCS concern regarding viral-derived peptide safety evidence
  • Limited long-term human safety data

Safety Score

35

Caution

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.