S-FROG PENTAPEPTIDE-1 (CYCLO OCTENYL TRIPEPTIDE-111) S-FROG PENTAPEPTIDE-2

About S-FROG PENTAPEPTIDE-1 (CYCLO OCTENYL TRIPEPTIDE-111) S-FROG PENTAPEPTIDE-2

A proprietary synthetic peptide blend inspired by frog-skin peptide sequences. Novel class; cosmetic data is thin so default-cautious.

Detailed Analysis

This INCI describes a synthetic peptide preparation containing sequences inspired by frog (anuran) skin peptides. Amphibian skin is a rich source of biologically active peptides, including antimicrobial and signaling peptides, which have attracted cosmetic interest as signal peptides and actives. The "S-" prefix indicates synthetic (not directly extracted from animal tissue). The INCI as recorded bundles several peptide moieties, which is unusual and reflects a single proprietary product family. There is no CIR or SCCS review, and peer-reviewed cosmetic safety/efficacy data is limited to supplier materials. Typical use is expected at 0.0001-0.01% given peptide potency.

Skin Benefits

• ✓ Synthetic peptide designed from a frog skin-peptide template
• ✓ Proprietary anti-aging or conditioning positioning
• ✓ Low-concentration cosmetic use keeps systemic exposure minimal

Known Concerns

• ⚠ Highly proprietary synthetic peptide — no CIR or SCCS review
• ⚠ Amphibian-mimetic peptides can be bioactive at low concentrations (some are antimicrobial peptides)
• ⚠ Limited peer-reviewed safety data
• ⚠ Composition complexity — this INCI is actually a blend

References