S-DNA APTAMER-2
Antioxidant
Good
CAS Number: 2145134-87-6
About S-DNA APTAMER-2
A synthetic single-stranded DNA aptamer with high affinity for ascorbic acid, functioning as an antioxidant and UV filter in skincare formulations.
Detailed Analysis
s-DNA Aptamer-2 is a 32-nucleotide single-stranded DNA molecule that folds into a defined 3D structure with specific affinity for ascorbic acid. It is produced synthetically with defined sequence control. While DNA aptamers represent an emerging cosmetic technology, the 32-nucleotide size is below threshold for significant dermal penetration concerns. No EU restriction entries apply to synthetic DNA aptamers. The antioxidant function provides skin benefit, though the specific binding interaction with ascorbic acid is primarily relevant to formulation chemistry rather than direct skin effect.
What It Does
Skin Benefits
- ✓ Antioxidant function via ascorbic acid binding and stabilisation
- ✓ UV filter designation suggests potential photoprotective applications
Known Concerns
- ⚠ Novel cosmetic ingredient class — limited long-term safety data in dermal applications
- ⚠ Nucleotide sequences may act as immunostimulants in compromised skin barriers
Safety Score
Good
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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Download LuxSenseThis information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.