S-DECAPEPTIDE-40 NONAPEPTIDE-27

Antimicrobial

81

Good

About S-DECAPEPTIDE-40 NONAPEPTIDE-27

A 19-residue antimicrobial peptide combining two sequences, representing a newer class of cosmetic ingredients with some evidence of antimicrobial activity but limited safety documentation.

Detailed Analysis

s-Decapeptide-40 Nonapeptide-27 is a single-chain synthetic peptide of 19 amino acids combining Decapeptide-40 and Nonapeptide-27 sequences. It is listed in CosIng with an antimicrobial function, making it distinct from most cosmetic peptides which are primarily conditioning agents. The EU cosmetics regulation does not restrict this INCI name, but its antimicrobial classification means it may require more careful assessment for microbiome disruption.

What It Does

ANTIMICROBIAL

Skin Benefits

  • Antimicrobial function
  • Skin conditioning
  • Potential preservative-sparing effect in formulations

Known Concerns

  • Newer ingredient with limited cosmetic safety history
  • Antimicrobial mechanism raises potential for skin microbiome disruption

Safety Score

81

Good

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.