P-PHENYLENEDIAMINE HCL

Other

38

Caution

CAS Number: 624-18-0

About P-PHENYLENEDIAMINE HCL

A highly restricted hair dye intermediate with severe sensitization risks, permitted only in oxidative hair dye formulations under strict EU controls.

Detailed Analysis

p-Phenylenediamine hydrochloride is the salt form of the primary hair dye intermediate PPD, classified under EU Annex III restriction III/8a. The SCCS has determined that PPD derivatives present high sensitization risk, and the EU cosmetics regulation requires specific labeling and handling precautions. This ingredient is prohibited for use in eyelash and eyebrow products (Regulation EU 2017/745) and is restricted to professional use oxidative hair dye formulations only in the EU market. Consumer self-application products face particular regulatory scrutiny.

Known Concerns

  • Severe skin sensitization risk (H317)
  • EU Annex III restricted - III/8a (oxidative hair dye only)
  • Prohibited for eyelash/eyebrow products
  • Professional use restrictions apply in EU

Safety Score

38

Caution

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.