P-METHYLAMINOPHENOL SULFATE

Other

42

Caution

CAS Number: 150-75-4

About P-METHYLAMINOPHENOL SULFATE

Also known as Metol — a hair dye chemical restricted in the EU. A known skin sensitizer that can cause allergic reactions, approved only for oxidative hair coloring with strict limits.

Detailed Analysis

P-Methylaminophenol Sulfate (Metol, CAS 150-75-4) is an aromatic amine used as an oxidation hair dye. It is listed in EU Annex III/223 with restricted conditions of use. Classified as a skin sensitizer (R43) and harmful with prolonged oral exposure (R48/22). Typically used at 0.1-1% in oxidative hair dyes. The SCCS has assessed it and deemed it safe only within Annex III conditions. It requires careful formulation and allergy testing before use. PubChem CID: 5931.

Known Concerns

  • Known skin sensitizer — can cause allergic contact dermatitis
  • EU Annex III restricted
  • Harmful with prolonged oral exposure
  • Hair dye only — strictly limited application
  • Requires allergy patch test before use

Safety Score

42

Caution

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.