N-(2-nitrophenyl)phosphoric triamide

About N-(2-nitrophenyl)phosphoric triamide

N-(2-nitrophenyl)phosphoric triamide is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Detailed Analysis

N-(2-Nitrophenyl)phosphoric triamide is an organophosphorus compound featuring a nitro-substituted phenyl ring attached to a phosphoric triamide scaffold. The 2-nitrophenyl group is a well-known structural alert in aromatic toxicity, associated with methaemoglobin formation and oxidative stress. The combined hazard profile — reprotoxicity (H360), acute oral and dermal toxicity (H302, H312), skin/eye/respiratory irritation (H315, H319, H332, H335), specific organ toxicity (H373), and aquatic hazard (H412) — makes this compound completely unsuitable for cosmetic use. No EU CosIng entry or safety assessment exists for this ingredient.

Known Concerns

• ⚠ H302: Harmful if swallowed
• ⚠ H312: Harmful in contact with skin
• ⚠ H315: Causes skin irritation
• ⚠ H317: May cause allergic skin reaction
• ⚠ H319: Causes serious eye irritation
• ⚠ H332: Harmful if inhaled
• ⚠ H335: May cause respiratory irritation
• ⚠ H360: May damage fertility or the unborn child
• ⚠ H373: May cause damage to organs through prolonged or repeated exposure
• ⚠ H412: Harmful to aquatic life with long-lasting effects

References