GALLOYL HEXAPEPTIDE-48

Antioxidant

80

Good

About GALLOYL HEXAPEPTIDE-48

A peptide conjugated with gallic acid that offers antioxidant benefits but may cause mild irritation in sensitive skin.

Detailed Analysis

Galloyl Hexapeptide-48 is a synthetic peptide conjugate combining gallic acid (a naturally occurring polyphenol found in tea, gallnuts, and other plants) with Hexapeptide-48. Gallic acid exhibits strong antioxidant and anti-inflammatory properties but can act as a mild skin sensitizer at high concentrations. The peptide moiety moderates this effect, resulting in a product with antioxidant and skin-protecting benefits and a favorable safety profile at cosmetic use levels. EU Annex III does not restrict gallic acid at cosmetic concentrations.

What It Does

ANTIOXIDANT SKIN PROTECTING

Skin Benefits

  • Antioxidant
  • Anti-inflammatory
  • Anti-aging
  • Skin conditioning
  • Soothing

Known Concerns

  • Potential mild sensitization at high concentrations due to gallic acid content
  • May cause irritation in individuals with polyphenol sensitivity

Safety Score

80

Good

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.