6-Nitro-o-toluidine
Other
Avoid
CAS Number: 570-24-1
About 6-Nitro-o-toluidine
A nitro-substituted aromatic amine with significant mutagenicity and carcinogenicity concerns, subject to severe EU restrictions as a hazardous intermediate.
Detailed Analysis
6-Nitro-o-toluidine (2-methyl-6-nitroaniline) is a nitroaromatic compound with significant safety concerns. Its PubChem safety score is 10, reflecting substantial toxicity. Nitroaromatic compounds are well-known for their mutagenic and carcinogenic properties. The structural alert from the nitro group combined with the aromatic amine creates multiple concerns for genetic damage and cancer. It is not permitted in cosmetic products under EU Regulation 1223/2009 due to severe safety concerns.
Known Concerns
- ⚠ Severe mutagenicity concerns
- ⚠ Suspected carcinogen (nitroaromatic)
- ⚠ EU banned/restricted substance
- ⚠ Significant genotoxic potential
Safety Score
Avoid
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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