5-ETHYL-3-HYDROXY-4-METHYLFURAN-2-ONE
Other
Moderate
CAS Number: 698-10-2
About 5-ETHYL-3-HYDROXY-4-METHYLFURAN-2-ONE
5-ethyl-3-hydroxy-4-methylfuran-2-one is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.
Detailed Analysis
5-Ethyl-3-hydroxy-4-methylfuran-2-one is a hydroxyfuranone (a lactone-like structure) used primarily as a flavoring agent (fruity, caramel notes) in foods. Its H302 classification (harmful if swallowed) indicates acute oral toxicity concern. In cosmetic applications, the furanone structure raises metabolic concerns due to potential for furan ring opening to reactive intermediates. EU SCCS notes insufficient data for chronic cosmetic safety of furanone derivatives. The ingredient is not currently restricted under EU Annexes but is flagged for further safety assessment.
Known Concerns
- ⚠ Acute oral toxicity (H302) - harmful if swallowed
- ⚠ Furan ring structure - potential for reactive metabolic intermediates
- ⚠ Limited chronic toxicity and sensitization data
- ⚠ Not evaluated by SCCS for cosmetic use
Safety Score
Moderate
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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