5,5'-Di-isopropyl-2,2'-dimethylbiphenyl-4,4'-diyl dihypoiodite (thymol iodide)
Caution
CAS Number: 552-22-7
About 5,5'-Di-isopropyl-2,2'-dimethylbiphenyl-4,4'-diyl dihypoiodite (thymol iodide)
An iodine-carrier antiseptic compound that releases thymol and iodine on skin contact, facing moderate regulatory restrictions due to sensitization potential and iodine exposure concerns.
Detailed Analysis
Thymol iodide (also known as thymol iodide or bithionol-free iodinated thymol) is an iodinated biphenyl compound that releases iodine and thymol upon contact with skin, providing antiseptic activity. It is listed in EU Annex III of Cosmetics Regulation 1223/2009 with specific restrictions on maximum concentration. Iodine-releasing compounds face regulatory scrutiny due to potential thyroid effects and contact dermatitis risk with repeated exposure.
Skin Benefits
- ✓ Antiseptic/disinfectant properties
- ✓ Broad-spectrum antimicrobial activity from iodine release
Known Concerns
- ⚠ Iodine release may affect thyroid function with extensive use
- ⚠ Skin sensitization potential
- ⚠ EU Annex III restricted compound
- ⚠ Potential for photoallergic reactions
Safety Score
Caution
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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