4'-tert-Butyl-2',6'-dimethyl-3',5'-dinitroacetophenone
Other
Caution
CAS Number: 81-14-1
About 4'-tert-Butyl-2',6'-dimethyl-3',5'-dinitroacetophenone
A nitrated ketone fragrance chemical (synthetic musk type) with moderate EU restrictions on maximum concentration across different product categories.
Detailed Analysis
This dinitroacetophenone derivative is a synthetic nitromusk fragrance subject to EU Annex III restrictions with different limits by product type: 1.4% in fine fragrance, 0.56% in eau de toilette, and 0.042% in other products. The nitro group on an aromatic ring in combination with skin sensitization potential limits its acceptability, and cumulative exposure from multiple fragrance sources is a concern under ongoing SCCS review.
Known Concerns
- ⚠ EU Annex III restricted — concentration limits by product category
- ⚠ Nitro-aromatic compound with sensitization potential
- ⚠ Cumulative nitromusk exposure under SCCS review
Safety Score
Caution
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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