4,4'-ISOPROPYLIDENEDIPHENOL/EPICHLOROHYDRIN COPOLYMER

Film Former

38

Caution

CAS Number: 25068-38-6

About 4,4'-ISOPROPYLIDENEDIPHENOL/EPICHLOROHYDRIN COPOLYMER

A film-forming epoxy polymer derived from bisphenol A (BPA) and epichlorohydrin, also known as bisphenol A diglycidyl ether (BADGE) polymer.

Detailed Analysis

This polymer is derived from the reaction of 4,4'-isopropylidenediphenol (bisphenol A, BPA — CAS 80-05-7) with epichlorohydrin (CAS 106-89-8), producing epoxy-type polymers. BPA is classified as a Substance of Very High Concern (SVHC) under EU REACH due to its endocrine-disrupting properties (reproductive toxicity, Category 1B). While the polymer-bound BPA significantly reduces bioavailability compared to free BPA, residual monomer traces must be controlled. Epichlorohydrin is classified as a Category 1B carcinogen and mutagen. The resulting copolymer is not individually restricted in EU Annexes II/III for cosmetic use, but the parental substances and their health classifications (SVHC, CMR) represent significant regulatory risk. EU has restricted BPA in cosmetic toys (Regulation 374/2014) and it is a candidate for wider restriction.

What It Does

FILM FORMING

Skin Benefits

  • excellent film-forming and adhesive properties
  • provides durable coating for nail and skin applications

Known Concerns

  • BPA component is a known endocrine disruptor — classified as SVHC under EU REACH (Category 1B reproductive toxin)
  • epichlorohydrin monomer is a Category 1B carcinogen and mutagen
  • residual BPA and epichlorohydrin monomers must be controlled and monitored
  • BPA increasingly restricted across EU product categories; regulatory risk is elevated

Safety Score

38

Caution

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.