3,5,6-TRIMETHYL-3-CYCLOHEXENYL-4-PENTEN-3-ONE

38

Caution

CAS Number: 67801-32-5

About 3,5,6-TRIMETHYL-3-CYCLOHEXENYL-4-PENTEN-3-ONE

3,5,6-TRIMETHYL-3-CYCLOHEXENYL-4-PENTEN-3-ONE is a cosmetic ingredient used in product formulation. Exercise caution due to limited available safety data.

Detailed Analysis

This trimethylcyclohexenyl ketone is a sesquiterpenoid-type fragrance compound with multiple sites of unsaturation. The H315 (skin irritation) and H317 (skin sensitization) classifications indicate it can act as a contact allergen. The alpha,beta-unsaturated ketone system (conjugated enone) is a structural alert for Michael acceptor reactivity, which correlates with sensitizing potential. The compound would require declaration as a fragrance allergen under EU rules and should be limited to low concentrations in leave-on products.

Skin Benefits

  • Complex fragrance profile for fine fragrances

Known Concerns

  • H315 - skin irritant
  • H317 - skin sensitizer
  • Alpha,beta-unsaturated ketone structural alert
  • Must be declared as fragrance allergen in EU

Safety Score

38

Caution

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.