(2-Isopropylpent-4-enoyl)urea (apronalide)

55

Moderate

CAS Number: 528-92-7

About (2-Isopropylpent-4-enoyl)urea (apronalide)

A urea derivative (apronalide) with mild acute toxicity but limited overall hazard data, used primarily as a sedative and not typically in cosmetics.

Detailed Analysis

(2-Isopropylpent-4-enoyl)urea (apronalide) is a ureide compound that is primarily known as a sedative/hypnotic drug (non-barbiturate). It carries only H302 (acute toxicity) as a classified hazard. It is not listed in EU cosmetic regulation Annexes, meaning it has no formal restriction, but its pharmaceutical background suggests limited use in cosmetics. The unsaturated acyl group could contribute to reactivity. The overall hazard profile is relatively favorable compared to many ingredients in this batch.

Known Concerns

  • ⚠ Limited cosmetic application data
  • ⚠ Drug compound background

Safety Score

55

Moderate

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.