2,3-Dinitrotoluene

5

Avoid

CAS Number: 602-01-7

About 2,3-Dinitrotoluene

2,3-dinitrotoluene is a cosmetic ingredient. Raw material is classified as a suspected carcinogen. Exercise caution due to limited available safety data.

Detailed Analysis

2,3-Dinitrotoluene (CAS 602-01-7) is a nitro-substituted toluene derivative that has been used in chemical synthesis. EU Regulation 1223/2009 Annex II prohibits the use of dinitrotoluenes in cosmetic products. The compound carries extensive hazard statements including H301/H311/H331 (toxic if swallowed, in contact with skin, or if inhaled), H341 (suspected genetic defects), H350 (may cause cancer), H361 (reproductive toxicity), H370/H372 (organ toxicity), and H400/H410 (aquatic toxicity). 2,3-Dinitrotoluene is metabolically activated to reactive intermediates that form DNA adducts, explaining its mutagenic and carcinogenic potential.

Known Concerns

  • ⚠ EU Annex II banned - nitroaromatic carcinogen
  • ⚠ Metabolic activation to DNA-damaging intermediates
  • ⚠ Confirmed mutagen (H341)
  • ⚠ Reproductive toxicity (H361)
  • ⚠ Acute toxicity by multiple routes
  • ⚠ Bioaccumulative potential

Safety Score

5

Avoid

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.