2,3-Dihydro-1H-indole-5,6-diol and its hydrobromide salt (see note 17).

Other

55

Moderate

CAS Number: 29539-03-5 - 138937-28-7

About 2,3-Dihydro-1H-indole-5,6-diol and its hydrobromide salt (see note 17).

A dihydroxyindoline hair dye precursor — gradually builds natural-looking color. Restricted to 2.0% in hair products.

Detailed Analysis

2,3-Dihydro-1H-indole-5,6-diol is an indoline derivative that acts as an auto-oxidative hair dye — it gradually darkens hair through air oxidation to form melanin-like polymers. It is restricted to 2.0% maximum in hair dye products. No GHS hazard classifications are recorded, suggesting relatively low acute toxicity compared to other hair dye chemicals. However, limited long-term safety data exists.

What It Does

HAIR DYEING

Known Concerns

  • EU restricted to 2.0%
  • Hair dye chemical
  • Limited long-term data

Safety Score

55

Moderate

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

Check your products for 2,3-Dihydro-1H-indole-5,6-diol and its hydrobromide salt (see note 17).

Scan any cosmetic product to see if it contains this ingredient and get a full safety breakdown.

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.