1,2-Benzenedicarboxylic acid, dihexyl ester, branched and linear

Other

28

Avoid

CAS Number: 68515-50-4

About 1,2-Benzenedicarboxylic acid, dihexyl ester, branched and linear

A phthalate plasticizer (dihexyl phthalate) that is restricted in the EU cosmetics regulation due to proven reproductive toxicity and is prohibited in cosmetic products.

Detailed Analysis

1,2-Benzenedicarboxylic acid, dihexyl ester, branched and linear (Di-n-hexyl phthalate, DnHP) is listed in CosIng with severe restrictions: it shall not be placed on the market or used in concentrations ≥0.1% by weight, and shall not be used as a propellant in aerosols. DnHP is classified as a Reproductive Toxicity Category 1B substance under EU CLP regulation (H360FD: May damage fertility and the unborn child). It is regulated under EU REACH as a substance of very high concern (SVHC) due to its reproductive toxicity. This ingredient would not be intentionally added to modern cosmetic formulations.

Known Concerns

  • EU REACH SVHC (Substance of Very High Concern) — reproductive toxicity
  • EU CosIng restriction: prohibited at ≥0.1% in cosmetic products
  • May cause endocrine disruption at low-level environmental exposures
  • Persistent and bioaccumulative in the environment

Safety Score

28

Avoid

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.