[[1,1'-Biphenyl]-4,4'-diyl]diammonium sulphate

12

Avoid

CAS Number: 531-86-2

About [[1,1'-Biphenyl]-4,4'-diyl]diammonium sulphate

A cosmetic ingredient. Exercise caution due to limited available safety data.

Detailed Analysis

Benzidine-4,4'-diammonium sulfate is an aromatic diamine salt derived from benzidine, a known human carcinogen. While this specific salt may have reduced direct carcinogenicity compared to benzidine itself, the EU Cosmetics Regulation Annex III restricts its use at ≥0.1% in cosmetic products due to concerns related to potential benzidine release. The restriction reflects the precautionary principle regarding aromatic amine carcinogens in consumer products.

Known Concerns

  • ⚠ Potential benzidine release concern
  • ⚠ Carcinogen precursor
  • ⚠ Restricted to ≤0.1% in EU cosmetics

Safety Score

12

Avoid

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.